How Long Does PRF Last Compared to Traditional Fillers?

If you’re exploring options to smooth wrinkles, restore volume, or improve skin quality, you may have come across PRF and traditional dermal fillers. Both treatments address volume loss and signs of aging, but they work in different ways and have different timelines for results.

Traditional fillers like Restylane®, JUVÉDERM®, and the RHA® Collection use synthetic hyaluronic acid (HA) to replace lost volume. Results are visible right away and can last 6–18 months, depending on the product and treatment area. PRF therapy (Platelet-Rich Fibrin therapy) uses your own blood’s platelets, fibrin, and growth factors to stimulate natural collagen production and skin regeneration. Results develop gradually and can last longer because they rely on your body’s repair mechanisms.

At Medimorph Integrative Aesthetic Medicine, we offer both PRF EZ Gel and high-quality dermal fillers so patients can choose the option that best fits their needs.

How Long Does PRF Last?

PRF treatment for wrinkles and volume restoration is designed for gradual, natural-looking improvement. Here’s what to expect:

• Initial results: You may notice subtle changes within a few weeks, especially improved skin texture and hydration.
  
• Peak improvement: Collagen and elastin production increase over the next 3–6 months, giving your skin more firmness and volume.
  
• Duration: Most patients enjoy results for 12–18 months, with some noticing benefits lasting up to two years, depending on age, skin health, and lifestyle.
  

Since PRF uses your body’s natural healing process, results vary more than with fillers. However, the benefit is that improvements are biological you’re restoring tissue quality, not just filling space.

How Long Do Traditional Fillers Last?

Popular fillers like Restylane®, JUVÉDERM®, and the RHA® Collection remain some of the best fillers for face enhancement when you want immediate volume.

Typical timelines:

• Restylane-L, Restylane Lyft, Restylane Kysse, and Restylane Contour – 6–12 months
  
• Juvederm Ultra and Juvederm Voluma – 9–18 months
  
• RHA Redensity, RHA 2, RHA 3, RHA 4 – 12–15 months
  

Fillers are a great choice if you want:

• Immediate smoothing of wrinkles and folds
  
• Quick lip enhancement or cheek contouring
  
• Minimal waiting period before results
  

However, once the body metabolizes the HA gel, the results fade, and repeat treatments are needed to maintain the look.

Key Differences Between PRF and Traditional Fillers

Both PRF and traditional fillers can enhance facial appearance, but they differ in how they work, how long results last, and what they target.

PRF:

• Material: Made from your blood components (Platelet-Rich Fibrin therapy)
  
• Results Timeline: Develops gradually over 3–6 months
  
• Longevity: Lasts about 12–18 months, sometimes longer
  
• Treatment Goal: Stimulates regeneration, improves skin quality, and boosts collagen production.
  
• Allergy Risk: Very low since it uses your cells
  

Traditional Fillers:

• Material: Made with synthetic hyaluronic acid
  
• Results Timeline: Visible immediately after treatment
  
• Longevity: Lasts about 6–18 months, depending on the product used
  
• Treatment Goal: Replaces lost volume and smooths wrinkles
  
• Allergy Risk: Rare, but possible reaction to HA-based products

Which Is Right for You?

Choosing between PRF for skin rejuvenation and traditional fillers depends on your goals, preferences, and treatment areas.

PRF may be better if you want:

• A natural approach with no synthetic materials
  
• Gradual, subtle enhancement
  
• Improvement in skin texture, tone, and elasticity
  
• Long-term tissue quality improvement
  

Fillers may be better if you want:

• Immediate visible changes
  
• More dramatic volume restoration
  
• Defined contour in specific areas like cheeks or jawline
  

Some patients combine both for optimal results fillers for instant lift and PRF for long-term collagen support.

PRF Treatment in Cincinnati, OH at Medimorph

At Medimorph Integrative Aesthetic Medicine, we offer PRF EZ Gel – Natural Filler for a variety of concerns, including:

• Under-eye hollows and dark circles
  
• Smile lines and perioral wrinkles
  
• Thin or uneven lips
  
• Acne scars and uneven skin texture
  
• Mild skin laxity and volume loss
  

Our team can also pair PRF with microneedling or hair restoration treatments for enhanced results.

Why Choose Medimorph for PRF and Fillers?

• Comprehensive options – We offer both advanced PRF therapies and a full range of dermal fillers, including Restylane®, JUVÉDERM®, and RHA® Collection.
  
• Expert injectors – Our providers are trained in precision injection techniques to ensure natural results.
  
• Personalized plans – Every treatment plan is customized to your facial anatomy and goals.
  
• Natural, safe outcomes – Especially with PRF, you benefit from a 100% biocompatible solution using your cells.
  

For traditional filler options, visit our page on Dermal Fillers.

Maintaining Your Results

Whether you choose PRF or traditional fillers, you can extend your results with healthy skin habits:

• Use broad-spectrum sunscreen daily
  
• Avoid smoking, which accelerates collagen breakdown.
  
• Stay hydrated and follow a nutrient-rich diet
  
• Schedule maintenance treatments before the results fully fade
  

Your provider can recommend the ideal touch-up schedule based on your chosen treatment and desired results.

Final Thoughts – PRF or Fillers?

If you’re looking for an option that works with your body to restore skin health and volume, PRF therapy is an excellent choice. If you want instant results for a special event or significant volume restoration, traditional fillers might be a better fit. Many patients at Medimorph Integrative Aesthetic Medicine choose a combination for the most balanced, lasting results.

PRF typically lasts 12–18 months, while most fillers last 6–18 months. Your provider will help you decide which works best for your needs, lifestyle, and budget.

 Restore Naturally – Book Now to schedule your consultation for PRF treatment in Cincinnati, OH, and explore all available options.